Strife is an upcoming MOBA being develop by S2Games which currently accepting applications for Close-Beta Testing. This is second MOBA game from S2 (first is Heroes of Newerth) which pretty much baffled me on idea of making another game of the genre they already have.
Some people are commenting that this game is a mixture of League of Legends and Heroes of Newerth. IMO, I think let's give this game a chance and don't hurdle into conclusions. They said it will have different mechanics differ from the other current MOBAs.
You can sign up for CBT here: http://strife.com/